Publications
- Probe Lasso: a novel method to rope in differentially methylated regions with 450K DNA methylation data.
Methods (San Diego, Calif.). 2015 Jan 15;72:21-8
Authors: Butcher LM, Beck S
- Epigenetics markers of metastasis and HPV-induced tumorigenesis in penile cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research. 2015 Mar 1;21(5):1196-206
Authors: Feber A, Arya M, de Winter P, Saqib M, Nigam R, Malone PR, Tan WS, Rodney S, Lechner M, Freeman A, Jameson C, Muneer A, Beck S, Kelly JD
- Comparative methylome analysis identifies new tumour subtypes and biomarkers for transformation of nephrogenic rests into Wilms tumour.
Genome medicine. 2015;7(1):11
Authors: Charlton J, Williams RD, Sebire NJ, Popov S, Vujanic G, Chagtai T, Alcaide-German M, Morris T, Butcher LM, Guilhamon P, Beck S, Pritchard-Jones K
- Nanobodies and nanocrystals: highly sensitive quantum dot-based homogeneous FRET immunoassay for serum-based EGFR detection.
Small (Weinheim an der Bergstrasse, Germany). 2014 Feb 26;10(4):734-40
Authors: Wegner KD, Lindén S, Jin Z, Jennings TL, el Khoulati R, van Bergen en Henegouwen PM, Hildebrandt N
- ChAMP: 450k Chip Analysis Methylation Pipeline.
Bioinformatics (Oxford, England). 2014 Feb 1;30(3):428-30
Authors: Morris TJ, Butcher LM, Feber A, Teschendorff AE, Chakravarthy AR, Wojdacz TK, Beck S
- Lanthanides and quantum dots as Förster resonance energy transfer agents for diagnostics and cellular imaging.
Inorganic chemistry. 2014 Feb 17;53(4):1824-38
Authors: Geißler D, Linden S, Liermann K, Wegner KD, Charbonnière LJ, Hildebrandt N
- Using high-density DNA methylation arrays to profile copy number alterations.
Genome biology. 2014 Feb 3;15(2):R30
Authors: Feber A, Guilhamon P, Lechner M, Fenton T, Wilson GA, Thirlwell C, Morris TJ, Flanagan AM, Teschendorff AE, Kelly JD, Beck S
- C2c: turning cancer into chronic disease.
Genome medicine. 2014;6(5):38
Authors: Beck S, Ng T
- Fourth-generation sequencing in the cell and the clinic.
Genome medicine. 2014;6(4):31
Authors: Mignardi M, Nilsson M
- Personalized medicine approaches for colon cancer driven by genomics and systems biology: OncoTrack.
Biotechnology journal. 2014 Sep;9(9):1104-14
Authors: Henderson D, Ogilvie LA, Hoyle N, Keilholz U, Lange B, Lehrach H, OncoTrack Consortium
- Methylome analysis identifies a Wilms tumor epigenetic biomarker detectable in blood.
Genome biology. 2014 Aug 19;15(8):434
Authors: Charlton J, Williams RD, Weeks M, Sebire NJ, Popov S, Vujanic G, Mifsud W, Alcaide-German M, Butcher LM, Beck S, Pritchard-Jones K
- Epigenetic noise fuels cancer evolution.
Cancer cell. 2014 Dec 8;26(6):775-6
Authors: Swanton C, Beck S
- Assessment of patient-derived tumour xenografts (PDXs) as a discovery tool for cancer epigenomics.
Genome medicine. 2014;6(12):116
Authors: Guilhamon P, Butcher LM, Presneau N, Wilson GA, Feber A, Paul DS, Schütte M, Haybaeck J, Keilholz U, Hoffman J, Ross MT, Flanagan AM, Beck S
- O-1602, an atypical cannabinoid, inhibits tumor growth in colitis-associated colon cancer through multiple mechanisms.
Journal of molecular medicine (Berlin, Germany). 2013 Apr;91(4):449-58
Authors: Kargl J, Haybaeck J, Stančić A, Andersen L, Marsche G, Heinemann A, Schicho R
- Six-color time-resolved Förster resonance energy transfer for ultrasensitive multiplexed biosensing.
Journal of the American Chemical Society. 2013 Jan 23;135(3):1102-9
Authors: Geißler D, Stufler S, Löhmannsröben HG, Hildebrandt N
- Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma.
Genome medicine. 2013;5(2):15
Authors: Lechner M, Fenton T, West J, Wilson G, Feber A, Henderson S, Thirlwell C, Dibra HK, Jay A, Butcher L, Chakravarthy AR, Gratrix F, Patel N, Vaz F, O'Flynn P, Kalavrezos N, Teschendorff AE, Boshoff C, Beck S
- Parallel visualization of multiple protein complexes in individual cells in tumor tissue.
Molecular & cellular proteomics : MCP. 2013 Jun;12(6):1563-71
Authors: Leuchowius KJ, Clausson CM, Grannas K, Erbilgin Y, Botling J, Zieba A, Landegren U, Söderberg O
- In situ sequencing for RNA analysis in preserved tissue and cells.
Nature methods. 2013 Sep;10(9):857-60
Authors: Ke R, Mignardi M, Pacureanu A, Svedlund J, Botling J, Wählby C, Nilsson M
- Integrated virus-host methylome analysis in head and neck squamous cell carcinoma.
Epigenetics. 2013 Sep;8(9):953-61
Authors: Wilson GA, Lechner M, Köferle A, Caren H, Butcher LM, Feber A, Fenton T, Jay A, Boshoff C, Beck S
- In situ mutation detection and visualization of intratumor heterogeneity for cancer research and diagnostics.
Oncotarget. 2013 Dec;4(12):2407-18
Authors: Grundberg I, Kiflemariam S, Mignardi M, Imgenberg-Kreuz J, Edlund K, Micke P, Sundström M, Sjöblom T, Botling J, Nilsson M
- In situ detection of individual mRNA molecules and protein complexes or post-translational modifications using padlock probes combined with the in situ proximity ligation assay.
Nature protocols. 2013 Feb;8(2):355-72
Authors: Weibrecht I, Lundin E, Kiflemariam S, Mignardi M, Grundberg I, Larsson C, Koos B, Nilsson M, Söderberg O
- SUMOylation in carcinogenesis.
Cancer letters. 2012 Mar 28;316(2):113-25
Authors: Bettermann K, Benesch M, Weis S, Haybaeck J
- Quantum dots as simultaneous acceptors and donors in time-gated Förster resonance energy transfer relays: characterization and biosensing.
Journal of the American Chemical Society. 2012 Jan 25;134(3):1876-91
Authors: Algar WR, Wegner D, Huston AL, Blanco-Canosa JB, Stewart MH, Armstrong A, Dawson PE, Hildebrandt N, Medintz IL
- Opportunities for sensitive plasma proteome analysis.
Analytical chemistry. 2012 Feb 21;84(4):1824-30
Authors: Landegren U, Vänelid J, Hammond M, Nong RY, Wu D, Ullerås E, Kamali-Moghaddam M
- Methylome analysis using MeDIP-seq with low DNA concentrations.
Nature protocols. 2012 Mar 8;7(4):617-36
Authors: Taiwo O, Wilson GA, Morris T, Seisenberger S, Reik W, Pearce D, Beck S, Butcher LM
- DNA-assisted protein detection technologies.
Expert review of proteomics. 2012;9(1):21-32
Authors: Nong RY, Gu J, Darmanis S, Kamali-Moghaddam M, Landegren U
- Automated genotyping of biobank samples by multiplex amplification of insertion/deletion polymorphisms.
PloS one. 2012;7(12):e52750
Authors: Mathot L, Falk-Sörqvist E, Moens L, Allen M, Sjöblom T, Nilsson M
- Semiconductor quantum dots for in vitro diagnostics and cellular imaging.
Trends in biotechnology. 2012 Jul;30(7):394-403
Authors: Jin Z, Hildebrandt N
- Fluorescence in nanobiotechnology: sophisticated fluorophores for novel applications.
Small (Weinheim an der Bergstrasse, Germany). 2012 Aug 6;8(15):2297-326
Authors: Hötzer B, Medintz IL, Hildebrandt N
- Resources for methylome analysis suitable for gene knockout studies of potential epigenome modifiers.
GigaScience. 2012 Jul 12;1(1):3
Authors: Wilson GA, Dhami P, Feber A, Cortázar D, Suzuki Y, Schulz R, Schär P, Beck S
- The parallel universe: microRNAs and their role in chronic hepatitis, liver tissue damage and hepatocarcinogenesis.
Swiss medical weekly. 2011 Oct 24;141:w13287
Authors: Haybaeck J, Zeller N, Heikenwalder M
- Biofunctional quantum dots: controlled conjugation for multiplexed biosensors.
ACS nano. 2011 Jul 26;5(7):5286-90
Authors: Hildebrandt N